With all the recent talk about human growth hormone (HGH), many people are asking the question, does HGH build muscle? The simple answer is yes, HGH builds muscle mass. In addition, it also can result in weight loss, increased bone strength, and more energy. However, it should be noted that HGH also has a variety of negative side effects as well. HGH can cause carpal tunnel syndrome, high blood pressure, and hyperglycemia. It is recommended that you talk to a doctor before taking HGH.